Read e-book online Annual Review of Immunology Volume 11 1993 PDF

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DIFFERENTIAL REGULATIONOF T LYMPHOCYTES 41 cells. After initial stimulation, naive T cells secrete only IL-2. Thesecells proliferate and develop by 4 days into effector cells that can be restimulated to secrete much hi. larger quantities of several different lymphokinesand to becomePgp-1 Expression of Mel-14 is variable, and cells maylose expression of CD45RB (20). Conditions following initial stimulation of T cells in intact animals apparently influence the nature of the effector cells generated and the kinds of lymphokines produced on restimulation (reviewed in 6).

Copenhagen:Munksgaard 15. Rapaport, F. , Lawrence, H. , Converse,J. M, Tiller, W. , Mulholland,J. H. J. Clin. Invest. 41:2166 16. J. J. 1967. A proposal for international cooperation in organ transplantation: Eurotransplant. In: 27 Histocompatibility Testing 1967. Baltimore: Williams& Wilkins 17. , Miggiano, V. , Ceppellini,R. Cell mediated lympholysisin manafter sensitization of effector lymphocytesthrough mixed leukocytecultures. G. Baet. Virol. Immunol. 64:243 18. Bach,F. , Hirschhorn,K. 1964.

AI~ENT ACTIVATED CDS+ CTLPRESENT ADHERENT CELLS ASAPCs B CELLS ASAPCs ANTIGEN UPTAKE BYPINOCYTOSI$ ANTIGEN REQUIRING PHAGOCYTO$1S "NAIVE" HTL LOWDOSECYCLOSPORIN INTRAC~LULAR PATHOGENS A DOSE LOWANTIGEN PRECURSORHIGHANTIGEN Annu. Rev. Immunol. 11:29-48. org by HINARI on 08/30/07. For personal use only. :~:~::~:~:. ,,/ ~’INTERM ~"ACTIVATED" EDIAT~ MATURE TH1 Figure 1 Factors predicted MATURE TH2 to favor or inhibit activation of TH 1 and TH2clones. [Modified from a figure published previously (36)] site of primary sensitization.

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