By C. L. Wellington, B. R. Leavitt (auth.), Prof. Y. Mizuno, Prof. D. B. Calne, Dr. R. Horowski, Prof. W. Poewe, Prof. P. Riederer, Prof. M. B. H. Youdim (eds.)
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Additional resources for Advances in Research on Neurodegeneration: Volume 7
1998). , 1999). , 1999). , 1997). Alternatively, cytochrome c might be released through a channel of the PT pore after conformational changes or through as yet unidentified channels, opening of which must depend on PT pore opening. It has also been suggested that Bax might form large pores through which cytochrome c is able to pass. , 1998). We have described that Bcl-2 closes VDAC to prevent cytochrome c release. , 1998). Regulation of activities of BcI-2 family proteins: BcI-2 family proteins constitute a possible convergence point for various life-death signals?
Whittingham and Rowland, London Pinna LA (1990) Casein kinase 2: An "eminence grise" in cellular regulation? Biochim Biophys Acta 1054: 267-284 Polymeropoulos MH, Higgins JJ, Golbe LI, Johnson WG, Ide SE, Di Iorio G, Stenroos ES, Pho LT, Schaffer AA, Lazzrini AM, Nussbaum RL, Duvoisin RC (1996) Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 274: 11971199 Polymeropoulos MH, Lavedan C, Laroy E, Ide SE, Dehejia A, Pike ADB, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Irio G, Globe LI, Nussbaum RL (1997) Mutations in the a-synuclein gene identified in families with Parkinson's disease.
JST), Suita, Osaka, Japan Summary. Apoptosis is an essential physiological cell death for selective elimination of cells, involved in a variety of biological events including morphogenesis, cell turn over and removal of harmful cells. Disruption of the regulation of apoptosis may result in various diseases, including cancer and autoimmune diseases both associated with inhibition of apoptosis and various degenerative disorders associated with enhancement of apoptosis, and therefore , apoptosis is an improtant theme in the medical field.
Advances in Research on Neurodegeneration: Volume 7 by C. L. Wellington, B. R. Leavitt (auth.), Prof. Y. Mizuno, Prof. D. B. Calne, Dr. R. Horowski, Prof. W. Poewe, Prof. P. Riederer, Prof. M. B. H. Youdim (eds.)